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The choice between these options often comes down to availability, cost, and individual response
In clinical trials, both exenatide and lixisenatide reduced body weight by 2.03.8 kg and reduced HbA 1c levels by 0.51.5% (5.51.6 mmol/mol) [23,24,25]
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Overexpression of IRP2 or MPP + treatment significantly enhances the binding of IRP2 to p53 in PC-12 cells, upregulates p53 levels, downregulates SLC7A11 expression, and increases arachidonate 12-Lipoxygenase (ALOX12) expression, thereby promoting ferroptosis and amino acid antioxidant system disruptions, elevating MDA levels, and inducing PC-12 cell damage
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