UK availability will depend on MHRA review and approval, and timelines haven't been confirmed
ANAL FISSURE TREATMENT Medical and surgical treatments are aimed at reducing the tone of the internal sphincter muscle, leading to pain relief and healing of the anal fissure

A first-degree, second-degree, third-degree relative of the individual, or of a dependent of the individual is defined as: First-degree relatives include an individual's parents, siblings, and children Second-degree relatives include an individual's grandparents, grandchildren, uncles, aunts, nephews, nieces, and half-siblings Third-degree relatives include an individual's great-grandparents, great grandchildren, great uncles/aunts, and first cousins Other resources Melanoma UK Melanoma Focus, including advice for Primary Care Health Professionals from Cancer Nurse Specialists on any matters pertaining to melanoma Cancer research UK Disclaimer - the author PCDS cannot accept responsibility for any misleading or incorrect statements, and the management of individual patients remains the direct responsibility of the individual doctor
Fatigue is a common side effect, which is why one-on-one supervision is vital