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Weeks 13 and beyond (1.0 to 2.4 mg maintenance) Once you reach your maintenance dose, your body has adapted and eating patterns stabilize

With that said, Research has shown that after 26 weeks, participants lost an average of 5lbs to just over 8lbs

If we treat 14 mg oral as roughly comparable to 0.5 mg weekly injectable Ozempic for orientation, then an older patient on oral tablets loses about 3.7 kg over the 30-ish weeks (bear in mind, evoke trials are 2 years long), and if around 45 percent of that loss is lean mass (or thereabouts) that is about 1.7 kg of muscle gone