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however, several hypotheses informed largely by evidence from related GLP-1 receptor agonist classes have been proposed: Weight loss-mediated reduction in vascular resistance , as excess adiposity is a well-established driver of hypertension

The medication's effect on gastric emptying may cause some individuals to feel uncomfortably full after eating, or to experience gastrointestinal symptoms such as nausea

They significantly reduce the risk of heart attacks, strokes and premature death in people who are already vulnerable," added Cork

Similarly, data from the SUSTAIN-6 study 35 , which compared the administration of semaglutide with placebo, revealed a notable nephroprotective function of GLP1-RAs