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For a comprehensive review of the mechanisms of CRPC development, the reader is referred to other excellent reviews 133,136,137,138,139
It supports injury recovery primarily by upregulating collagen and elastin synthesis, stimulating angiogenesis via VEGF and bFGF pathways, and broadly resetting gene expression in damaged tissue
A new Nature paper suggests common variants in GLP1R and GIPR influence weight loss and nausea or vomiting, but the effects are modest, and non-genetic factors such as drug choice, dose, duration, sex, diabetes status, and tolerability still matter greatly
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Rosenbaum M, Kissileff HR, Mayer LE, et al
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