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59 Another important advantage of eGFR estimates based on cystatin C is that they may better correlate with the risk of developing cardiovascular disease and premature mortality

The dosing ranges referenced are derived from preclinical research models and observational, non-clinical protocols

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One possible mechanism of action for such potentially protective actions against liver fibrosis may be the modulation of matrix metalloproteinase (MMP) activity and the apparent inactivation of tissue inhibitors of matrix metalloproteinase (TIMP)