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This additional indication was based on results from a multinational clinical trial showing that Wegovy reduced the risk of major adverse cardiovascular events (MACE) by 20%
Although, most participants lost weight, there was heterogenicity, that has been well-documented in obesity studies [66] and those with higher BMI above 35 experienced greater mean percentage weight loss [64]
Understanding how tirzepatide works can be key to recognizing its benefits
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