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A nested case-control study within the Singapore Chinese Health Study demonstrated a significant 57% reduction in colon cancer risk among high consumers of dietary isothiocyanates (ITCs) who carried the double null genotype, suggesting that compromised GST activity enhances the protective effect of ITCs like SFN (59)
It's also been studied for its potential to improve the outcomes for patients undergoing chemotherapy, as it may reduce some of the oxidative side effects associated with these treatments
Immunol., 96:104-109 (1994)
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