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Enrolling 17,604 adults aged 45 or older with established cardiovascular disease and a BMI of 27 or higher (without diabetes), SELECT showed that semaglutide 2.4 mg reduced the composite of cardiovascular death, nonfatal myocardial infarction, and nonfatal stroke by 20% over a mean follow-up of nearly 40 months
Personalized Restart: The Role of Genetic Insights in Your Restart Plan Not all patients respond to semaglutide equally, and genetic variation plays a measurable role in treatment outcomes
There was no difference between the groups in the number of procedural complications or adverse events
A typical loading dose is 1,000 mcg (1 mg) administered intramuscularly several times per week (such as every other day or 3 times per week) for a couple of weeks
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