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One such mechanism is hepatocyte apoptosis, a key feature of MASLD progression, particularly in metabolic dysfunction-associated steatohepatitis (MASH)

And they have a different relationship with growth hormone than fat cells elsewhere in the body

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The intracellular lactate dehydrogenase (LDH) activity of living cells is relatively constant during the culture, while impaired cells lead to LDH leakage to the culture medium ( 2 O 2 , either in the presence or absence of peptides, was determined by using the spectrophotometric method