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Legal Status & Regulatory Information Retatrutide remains an investigational peptide and has not been approved by the U.S
It activates the mTOR pathway, which stimulates muscle growth and regeneration
For obesity-specific data, the STEP trials showed semaglutide 2.4 mg producing roughly 15% body weight loss over 68 weeks
The dose can be increased in 2.5mg increments every 4 weeks as needed for glycemic control, with a maximum dose of 15mg
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