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Laboratory research record on Glutathione [PMID: 7326048] PubMed laboratory record discussing Glutathione in a research context

3.3 Iron metabolism Iron metabolism is inextricably linked to ferroptosis

The hydrophobic tail of LCACs can be inserted into the membrane and may trigger the nonspecific activation of signaling pathways in the inner mitochondrial membrane to modulate its function, providing new insights into the unique mechanism of action of acylcarnitines in mitochondrial homeostasis [25]

While these compounds are not direct ERAD modulators, their success highlights the importance of targeting ER stress in metabolic diseases