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TB-500 also appears to be generally well-tolerated, but again, safety data derived from adequately powered clinical trials is lacking

Naringenin confers multifaceted protective effects in TBI models by targeting neuroinflammation, oxidative stress, mitochondrial dysfunction, and excitotoxicity

The intracellular glutamate concentration is nearly 10-fold higher than the Km value, but intracellular cysteine concentrations approximate the apparent Km value [10] indicating that cysteine may be a limiting substrate for GCL

Peptides, or small protein fragments, are often too unstable to use as drugs, but in this study, the researchers also developed a way to stabilize the molecules and help them get into target cells