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No Phase 3 trials were undertaken
Many physicians choose to treat B12 deficiency with B12 shots because injections avoid the gastrointestinal tract entirely
Meanwhile, research on synergistic effects with other anti-aging substances will be further deepened, providing important support for establishing multi-target, multi-pathway anti-aging intervention systems
In other words, the preclinical signal appears against a backdrop of controlled energy intake and activity, not as a standalone effect that overrides diet
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