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In 1997, Robinson and Smyth reported the products and intermediates formed during the oxidation of L-tyrosine and L-dopa

Free radicals are formed by enzymes, such as nicotinamide adenine dinucleotide phosphate (NADPH) oxidase, nitric oxide synthase (NOS), xanthine oxidase (XO), cytochrome P450, cyclo-oxygenase (COX), and lipoxygenase [10]

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