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Key findings Related Stories Planetary Health Diet lowers cardiovascular risk in older women Three key brain regions interact during sleep to support memory formation Study links neighborhood visual traits to human sleep Within six months of starting GLP-1 therapy, the rate of hypotensive events increased from 8.7% to 10.2% The increased risk remained significant at 12 months, with hypotensive events rising from 13.6% to 14.3% Adults age 65 and older accounted for 53% of hypotensive events despite representing 37% of the study population Patients with Type 2 diabetes made up 75% of those experiencing hypotensive episodes but only 63% of the overall cohort In secondary analyses, the scientists found that weight loss alone did not explain the increased risk, suggesting other mechanisms of action may be at play Below is a Q&A with study senior author Dr
The prevailing model for NRF2-dependent target gene expression involves the binding of NRF2 to ARE sequences within proximal promoters of specific target genes (Tonelli et al, 2018)
Severe B12 deficiency is a health issue, not just feeling tired
doi:10.1001/jama.2025.15841
