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In this context, using a previously reported -helical peptide as a template sequence (Behera et al., 2022), this study discusses the rational computational design and in silico evaluation of an -helical peptide (SR18: 18 aa) as a potent agonist of GLP-1R, with native GLP-1 and Semaglutide serving as references
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Traditional sugars are notorious for spiking blood glucose, elevating insulin, and fueling cravings that lead to overconsumption
Conclusion: In middle-aged adults with longstanding T1D, increased diabetes distress was related to lower neuronal communication in the lower alpha band, specifically in networks comprising frontal, parietal, and temporal regions, which in previous literature has been related to stress and emotion regulation in other disorders
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