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IL-15 enhances insulin sensitivity, promotes lipid oxidation, and activates the PPAR- pathway in muscle, liver, and fat, improving glucose homeostasis and reducing inflammation
GSH dysregulation might cause global immune cell autophagy decline with increased generation of proinflammatory cytokines in aging, further provoked by mitochondrial ROS signaling (293)
MDD is also marked by systemic inflammation with high cytokines IL-6, TNF-, and IL-1 (Troubat et al., 2021)
Mills, G.C
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