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A large, population-based retrospective cohort study was conducted using the TriNetX platform, which provided real-time access to electronic health records of 634,265 adult patients with MASLD/MASH
Oscar Birkhan 2
In tirzepatide clinical trials, nausea occurred in approximately 25% of participants at therapeutic doses, while semaglutide trials reported similar or slightly higher rates depending on dose level
However, this acute oxidative stress serves as a hormetic stimulus that triggers adaptive responses, including upregulation of endogenous antioxidant systems including glutathione synthesis
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