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Meanwhile, new GLP-1/GIP dual receptor agonists have been proven effective in neuroprotection and mechanisms in PD, such as DA-JC1 (DA1), DA-JC4 (DA4), and DA-CH5 (DA5) in MPTP-induced PD models
Nanoplatform-based delivery systems address critical challenges related to BBB permeability and drug bioavailability, enhancing CNS targeting and sustained receptor activation
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