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Opioids Opioids mask pain through central nervous system effects but carry risks of tolerance, dependence, overdose, and paradoxical opioid-induced hyperalgesia
Precision Testing Evaluates Krebs cycle markers, fatty-acid oxidation, ketone pathways, and lactate/pyruvate balance to assess energy efficiency
The absence of established treatment protocols makes it difficult to determine optimal dosing regimens, treatment duration, and comprehensive monitoring requirements
Benjamin EJ, Blaha MJ, Chiuve SE, Cushman M, Das SR, Deo R, et al
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