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Chemistry & Structural Modification BPC-157 is a linear, non-glycosylated 15-residue peptide with sequence GEPPPGKPADDAGLV (one-letter) or Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val
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NPM1 mutations are known to result in aberrant cytoplasmic localization and downregulation of the NPM1 protein 28 , as observed in our data (log 2 fold change (FC): 0.44, P 0.2 for C3, C7 and C8)
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