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Tirzepatide activates both GLP-1 and GIP receptors, which may produce greater weight loss in some patients
But in appropriate cases, it can reduce medication burden and support long-term balance without rebound weight gain
While semaglutide consistently drives an average weight loss of over 15% across both pill and injectable forms, orforglipron yields a dose-dependent range of 7.511%
At the end of treatment, there was improvement in psoriasis severity and quality of life
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