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Moreover, the therapeutic potential of anti-TNFs has been also demonstrated in several disorders, such as Behcets disease (BD), sarcoidosis, Takayasu arteritis, idiopathic inflammatory myopathies, synovitis-acne-pustulosis-hyperostosis-osteitis (SAPHO) syndrome, polyarteritis nodosa, adenosine deaminase 2 deficiency (DADA2) and pyoderma gangrenosum [4,5,6,7,8,9,10,11]

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