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Ja Arah D, Al Zoubi MS, Abdelhady G, Rabi F, Tambuwala MM
a maximum of approximately 10% inhibition of COMT at 600 M (no curve could be fitted)
3 Expert Rev Clin Pharmacol Afamelanotide (CUV1647) in dermal phototoxicity of erythropoietic protoporphyria (Minder & Schneider-Yin, 2014)Reviews the -MSH receptor-mediated mechanism, the rationale for afamelanotide in protoporphyria, and the phase II/III and safety results, concluding the risk-benefit profile is favorable in this indication
In those cases, go for lighter serums or creams that include it in smaller amounts
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