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Recommended Dosage Typical dose : 515 mg per week, split into 23 injections Injection frequency : 23x weekly (e.g., Monday, Wednesday, Friday) Cycle length : 24 weeks on, followed by 24 weeks off Injection method : Subcutaneous (abdomen, thigh, or flank area) Beginners often start with 5 mg/week and titrate up based on response and tolerance
Nygrd O, Nordrehaug JE, Refsum H, Ueland PM, Farstad M, and Vollset SE (1997a)
Initial changes in skin hydration and surface texture typically appear between weeks 2 and 4
Ultimately, the decision to start these medications should be taken after an informed discussion with a physician who is astute to the benefits and adverse effects of these drugs and to indications and contraindications. Additionally, Dr
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