Binding of GLP-1 to GLP1R has multiple effects, including enhancing insulin secretion from pancreatic beta cells in response to glucose, increasing insulin expression, preventing beta-cell apoptosis, promoting the formation of new beta cells, reducing glucagon secretion, slowing down stomach emptying, promoting satiety, and improving glucose disposal in peripheral tissues
Providers should monitor weight trajectory , GI tolerability (nausea, vomiting, constipation) , signs of pancreatitis (persistent severe abdominal pain vomiting), gallbladder disease (RUQ pain, fever, jaundice), hydration/renal function when clinically indicated (risk of AKI with severe GI effects), blood pressure , and glucose metrics (especially if combined with insulin or sulfonylureas due to hypoglycemia risk)
It acts as a breath of fresh air for the epidermis, helping to even out skin tone and provide that coveted, healthy glow typically associated with a good nights rest
Comparing Eczema and Psoriasis Responses to GLP-1 Its worth distinguishing eczema from psoriasis in this context, since both are chronic inflammatory skin conditions but their underlying immunology differs in ways that may affect how they respond to GLP-1 medications