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PLPBP gene mutation and epilepsy The PLPBP gene, located on chromosome 8p11.23, encodes pyridoxal phosphate homeostasis protein (PLPHP), which is widely expressed in humans, and can be found in the mitochondria or cytoplasm
Larger randomized controlled trials as well as basic research studies are urgently needed to further explore the reproductive system pathogenesis induced by SSRIs and to identify better strategies for the use of SSRIs in treating diseases while also reducing their reproductive toxicity
Vaez et al., 2016
& Spranger, S
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