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Ubiquitin, cellular inclusions and their role in neurodegeneration

330 SMA is a genetic neuromuscular disease caused by the deletion or mutation of the survival motor neuron 1 (SMN1) gene, leading to the loss of alpha motor neurons and progressive muscle atrophy

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Figure 3 3.2 Identification and annotation of lung adenocarcinoma cell subpopulations Following rigorous quality control, normalization, and batch effect correction, we performed principal component analysis, and the results showed that cells from the two sample sources were highly intermixed in the two-dimensional coordinate space, with no distinct clustering or separation observed ( Figure 4A )