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Forty-six patients with IgA nephropathy at Kyoto University Hospital who underwent kidney biopsy between 2014 and 2018 were recruited (Table 1 and Supplemental Figure 1)

The highest peak yielded a contrast of 1.63

In adulthood however, dietary restrictions decreasing IIS may reduce the risk of age-associated pathology like proteotoxicity as recently demonstrated in a mouse model of Alzheimer disease [33]

Lack of baseline measurements for liver steatosis and fibrosis before the initiation of the EDICT study, as well as the small number of patients enrolled were the main limitations of this trial

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