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Moreover, exendin-4 inhibits NF-B activity by hindering the breakdown of IB (NF-kappa-B inhibitor alpha) in LPS-stimulated primary microglia, which reduces the activation of microglia and the generation of pro-inflammatory cytokines [113]
Goldberger said
While we cannot speculate on specific timelines or coverage decisions, it would be reasonable to expect there will be significant interest in the potential cost savings associated with the generic entries. Novo Nordisk Canada said in a statement that it is actively exploring a range of strategies to respond to evolving market conditions and patient needs and said it offers a savings program for some patients
