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Ribulose-5-phosphate either: Xylulose-5-phosphate (by ribulose-5-phosphate epimerase) or Ribose-5-phosphate (by ribose-5-phosphate isomerase) Xylulose-5-phosphate + ribose-5-phosphate glyceraldehyde-3-phosphate + sedoheptulose-7-phosphate Catalyzed by transketolase The reaction requires thiamine Thiamine Also known as thiamine or thiamin, it is a vitamin C12H17N4OSCl of the vitamin B complex that is essential to normal metabolism and nerve function and is widespread in plants and animals Water-soluble Vitamins and their Deficiencies pyrophosphate