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In the case of suspected cobalt hypersensitivity, an intradermal test dose should be administered because anaphylactic shock and death have followed parenteral administration of cyanocobalamin.
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Quick refresher: what B12 actually does Vitamin B12 (cobalamin) is a water-soluble vitamin involved in red blood cell formation, nervous system maintenance, and the methylation reactions that support energy metabolism
Oral therapy is not always effective, as some persons lack intrinsic factor, an endogenous substance produced by the stomach and necessary for oral B12 absorption
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