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It affects the GLP one receptor but also the GIP receptor, which are both involved in hunger and satiety and motility. Dan Azagury, MD, FACS, the chief bariatric surgeon and medical director of Stanford University School of Medicines Lifestyle and Weight Management Clinic in California, who also was not involved in the Eli Lilly study, told Healthline that he was not surprised at the studys results
How Glp-1 medications work Semaglutide/Tirzepatide activates GLP-1 and GIP receptors (Tirzepatide) to regulate appetite, reduce hunger, and promote sustainable weight loss under physician supervision
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