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Potential Effects of IGF-1 LR3 Based on current studies and reported use, the areas most often linked to IGF-1 LR3 applications are: Muscle growth Activation of the PI3K/AKT/mTOR pathway theoretically allows IGF-1 LR3 to aid in increased muscle protein synthesis and hypertrophy, particularly in combination with resistance training

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Crushed tissue samples of liver, kidney, and spleen were homogenized in 500 L of 0.15 M NaCl in 10 mM NaOH-HEPES buffer (pH 7.4) in a 1 mL glass Dounce homogenizer

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