The right trial would be in people w ithout any cognitive impairmen t but at high-risk as defined by family history, high polygenic risk score, APOE4 carrier or homozygotes, high levels of p-Tau217 and other blood biomarkers
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High adherence and strong completion rates supported the feasibility of administering oral semaglutide in an AUD-like context where drop-out can otherwise obscure signal
How can I reduce nausea while taking semaglutide Smaller meals, protein first eating, avoiding high fat foods, staying hydrated, and slow dose increases all help reduce nausea