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Primary Areas of Research and Potential Applications Pre-clinical research, primarily conducted in animal models such as rats, mice, and dogs, along with in vitro cell studies, has indicated a remarkably broad range of potential therapeutic applications for BPC-157

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As already highlighted, these glands have high GLP-1R expression in both rodents and humans, and liraglutide has been shown to upregulate genes encoding mucins in the Brunner's glands of mice (73, 87, 249), which may reduce intestinal permeability and improve systemic inflammation (250)