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Rushing through titration increases the likelihood of discontinuing treatment due to intolerable symptoms

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Clinical research supports modest, real gains, and results are most pronounced in men who have lost length from tissue atrophy or scarring related to erectile dysfunction or Peyronie's disease

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However, based on the populations studied in clinical trials to date, researchers have focused primarily on adults living with obesity typically defined as a body mass index (BMI) of 30 kg/m or above as well as those with overweight accompanied by at least one weight-related health condition, such as type 2 diabetes, hypertension, or dyslipidaemia

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