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J Biomed Opt 25:1

1 / 1 Vitamin B12 is an essential nutrient that supports a healthy nervous system and the production of red blood cells

Strategies targeting BH 4 regeneration via guanosine triphosphate cyclohydrolase (GPTCH) or the BH 2 -reducing enzyme, dihydrofolate reductase (DHFR), may help preserve eNOS function [139, 140]