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Finally, a number of inherited mutations in genes involved in carnitine shuttling and fatty acid oxidation pathways do not systematically result in carnitine depletion (such that carnitine supplementation may not help mitigate the symptoms) but lead to abnormal profiles of acylcarnitine esters in blood (35, 40)

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Preclinical studies have demonstrated that liraglutide significantly suppresses obesity-associated breast cancer cell proliferation via modulation of adipokine expression, with enhanced antineoplastic effects observed in obese populations [122]

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