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Mood Changes and Irritability The Stress Connection: Dallass high-pressure lifestyle already contributes to stress, but B12 deficiency can amplify mood issues, leading to: Increased irritability Anxiety Depression-like symptoms Mood swings B12 deficiency affects neurotransmitter production, which directly impacts mood regulation

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doi:10.1016/j.tem.2017.02.004 (PMID 28291578) Roberti A, Fernndez AF, Fraga MF