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Compared with placebo group, liraglutide increased subjects satiety, reduced intake of sweet, salty and high-fat foods, and increased plasma PYY level after meals

Yes, we need to pay attention to the [gastrointestinal] adverse events, but that is not the whole story. A great opportunity for future research Other key questions about GLP-1s that need to be answered are when or if it is appropriate to stop them, and why there is such wide variation in how patients respond to them

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Retatrutide's longest Phase 3 data is 80 weeks for TRIUMPH-1 (plus a 104-week extension in a BMI 35 subgroup)