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Gastro-oesophageal reflux is listed as a common side effect (up to 1 in 10 people) with some GLP-1 medications, particularly during initial dose titration
Numerous studies have demonstrated evidence of oxidative stress-induced mitochondrial abnormalities involved in cholestasis and a potential mechanism based on the altered mtDNA copy number and imbalance of oxidants versus antioxidants in the mitochondria (Iruzubieta et al., 2021)
It increases glucose uptake at a cellular level, bringing blood sugar levels down rather than up (as with GH)
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