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46 That dedicated kidney outcomes study, involving over 3500 patients with both T2D and established chronic kidney disease, demonstrated that once-weekly subcutaneous semaglutide 1.0 mg significantly reduced the primary composite renal outcome (including kidney failure onset, a 50% persistent decline in estimated glomerular filtration rate (eGFR), or renal/cardiovascular death) compared with placebo
Wanting to increase the dosage to break through a plateau Another common theme Katz cautions against is the desire to increase the dose to reduce appetite even further in order to shatter a plateau
Comparing doses online or through social media can lead to misconceptions
For example, if your Free T3 is in the low-normal range but your TSH is "fine," it might explain why you still feel tired despite your GP's assessment
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