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In vitro studies have examined its interaction with endothelial cell migration, fibroblast proliferation, and nitric oxide synthase (NOS) system modulation, documenting activation of the VEGFR2-Akt-eNOS and Src-Caveolin-1-eNOS signalling axes in vascular endothelial cells [1]
However, if the FDA ultimately reclassifies them and they are produced by compounding pharmacies in the U.S., clinicians would have discretion to write prescriptions outside of those narrow indications
Patients with LTBI are typically asymptomatic
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