Abdulghani AA, et al
It is synthesized intracellularly and exists in both reduced (GSH) and oxidized (GSSG) forms, with the ratio of these states serving as a key indicator of cellular redox balance that researchers use to assess oxidative stress in experimental systems
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however, it has less specificity than the newer HPLC-UV methods, which could account for some differences in levels of silymarin found (21)