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38 (Suppl 1), S122S127
Early Clinical Evidence (Small but Promising) A 2025 case series followed five women with lipedema and insulin resistance treated with the GLP-1 medication exenatide (Patton et al., 2025)
First, the FDA has not granted retatrutide Breakthrough Therapy designation as of May 2026, which means there is no built-in mechanism for an accelerated review
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