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Double-blind placebo-controlled study with PT-141 (MC4R-selective derivative of Melanotan II) 20 mg intranasally
Blood Collection and Biochemical Analysis At the end of the treatment period (21 days), blood samples (7ml) was obtained from the retro-orbital sinus of each animal under mild ether anaesthesia into a heparinised EDTA tubes to prevent coagulation
The selectivity is built into the molecule's structure, not just its dosing
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