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A study of long-term outcome of Spitz-type melanocytic tumors during a 15-year period found that of 157 patients with Spitz-type melanocytic lesions, atypical Spitz tumors were associated with an increased melanoma risk, minimal lethal potential, and moderate risk of metastasis to the regional lymph node basin [58]
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The clinical significance in healthy individuals using acetaminophen at recommended doses is modest
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