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Moreover, high eHSP72 levels have been linked to diabetic complications such as ketoacidosis, highlighting the importance of maintaining a finely tuned balance between intracellular and extracellular HSP72 for therapeutic intervention

FDA approved a new indication for semaglutide (Wegovy) to reduce the risk of cardiovascular death, myocardial infarction, and stroke in adults with CVD and either obesity or overweight ( 3.2 Neurological and psychosocial protection GLP-1RAs have demonstrated growing potential in neurological and psychosocial disorders

injections of 10 nmol kg 1 semaglutide ( n = 8 mice), 100 nmol kg 1 GLP-1MK-801 ( n = 8 mice) or vehicle (isotonic saline, n = 8 mice) at a volume of 5 l g 1

10,11 Notably, no serious AEs occurred in add-on trial